LARGE ARMORED BRIDGING OVER FRACTURED VERTEBRA WITH INTRASPINAL TUMOR MIMICKING BONY MASS CAUSED BY MIGRATED FRAGMENTS OF BURST CERVICAL VERTEBRA PRESENTING WITH SEVERE CERVICAL MYELOPATHY

Large armored bridging over fractured vertebra with intraspinal tumor mimicking bony mass caused by migrated fragments of burst cervical vertebra presenting with severe cervical myelopathy

Vertebral body may get displaced anterior or posteror with elements of rotation.However, burst cervical spine vertebral fracture may migrate anteriorly and posteriorly simultaneously.However anterior displaced fragment forming armor like mass is very rare.Similarly, the posteriorly propelled fragments migrating caudally and posterolaterally produci

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Impaired B Cell Function in Mice Lacking Perforin-2

Perforin-2 (P2) is a pore-forming protein with cytotoxic activity against intracellular bacterial pathogens.P2 knockout (P2KO) mice are unable to control infections and die from normally non-lethal bacterial infections.Here we show that P2KO mice as compared to WT mice show significantly higher levels of systemic inflammation, measured by inflammat

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Observational cohort study to validate SEARCH, a novel hierarchical algorithm to define long-term outcomes after pulmonary embolism

Background Chronic dyspnoea and exercise impairment are common after acute pulmonary embolism (PE) but are not defined and quantified sufficiently to serve as outcomes in clinical trials.The planned project will clinically validate a novel method to determine discrete, clinically meaningful diagnoses after acute PE.The method uses an algorithm enti

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